News Highlights

FDA

Thu May 8 21:30:07 2008 (NewsRx)
VitalCare Announces FDA Approval of Infusion Device Used for iCAT Therapy

Thu May 8 15:45:02 2008 (Yahoo AP)
FDA OKs Abilify for secondary use against bipolar disorder

Thu May 8 03:21:02 2008 (Osiris Therapeutics, Inc.)
Osiris Receives Approval for Use of Prochymal(TM) Under FDA Expanded Access Treatment Program

Thu May 8 00:09:09 2008 (Reuters)
FDA sets panel review of Glaxo clotting drug-Amgen

Clinical Trials

Wed May 7 16:33:19 2008 (Array BioPharma Inc.)
Array BioPharma Presents Additional Positive Phase 2 Results in Inflammatory Pain Clinical Trial at the American Pain Society's Annual Scientific Meeting

Tue May 6 22:33:14 2008 (LifeCycle Pharma A/S)
LifeCycle Pharma Announces Positive Data from LCP-AtorFen Phase II Clinical Program

Tue May 6 17:03:11 2008 (Poniard Pharmaceuticals, Inc.)
Poniard Pharmaceuticals Completes Enrollment of Phase 2 Picoplatin Trial in Colorectal Cancer

Mon May 5 23:03:17 2008 (Integrium, LLC)
Integrium Introduces Its Integrium Clinical Excellence (ICE) Methodology to Assure Consistent Delivery of Sponsor Clinical Trials

M&A and Other Deals

Fri May 9 04:24:17 2008 (EUSA Pharma Inc)
EUSA Pharma Completes Acquisition Of Cytogen Corporation

Thu May 8 17:36:17 2008 (NuVasive, Inc.)
NuVasive Signs Definitive Agreement to Acquire Osteocel Biologics Business from Osiris Therapeutics

Wed May 7 11:03:35 2008 (Regenesis Biomedical, Inc.; Advanced BioHealing, Inc.)
Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R)

Wed May 7 09:15:40 2008 (NGN Capital)
ACT Biotech Acquires Clinical and Early Stage Oncology Portfolio Licenses From Bayer Healthcare

Topic Specific

Cancer

Fri May 9 00:48:14 2008 (Cytopia Limited)
Cytopia Announces Novel Anti-Cancer Drug Development Collaboration

Thu May 8 21:18:07 2008 (University of Oklahoma)
New Cancer Gene Found

Thu May 8 13:57:14 2008 (Yahoo AP)
Ark. court: Cancer claim against poultry firms can proceed

Thu May 8 11:57:08 2008 (American Society of Plastic Surgeons)
Skin flaps deliver cancer-fighting therapy, ASPS study reveals

RNA

Wed May 7 18:12:14 2008 (Sigma-Aldrich)
Sigma-Aldrich Joins Phase 2 of The RNAi Consortium to Validate shRNA Libraries

Wed May 7 11:06:08 2008 (University of Florida)
MicroRNAs Appear Essential For Retinal Health

Wed Apr 30 11:36:36 2008 (Cequent Pharmaceuticals, Inc.)
Cequent Pharmaceuticals' Johannes Fruehauf, MD, Ph.D., to be Featured Speaker at RNAi World Congress in Boston - May 2, 2008

Tue Apr 29 02:09:45 2008 (PLoS: Biology)
High-Throughput SHAPE Analysis Reveals Structures in HIV-1 Genomic RNA Strongly Conserved across Distinct Biological States

Stem Cells

Tue May 6 02:45:06 2008 (Geron Corporation)
University of Edinburgh Human Embryonic Stem Cell Program Awarded UK Grant Funding

Wed Apr 30 15:33:06 2008 (Reuters Health)
New type of stem cells coaxed into heart tissue

Wed Apr 30 08:06:03 2008 (University of California - Los Angeles)
Stem Cell Researchers Create Heart And Blood Cells From Reprogrammed Skin Cells

Tue Apr 29 21:18:08 2008 (Journal of the National Cancer Institute)
Stem Cell-Like Cancer Cells Resistant To Standard Therapy, Responsive To Targeted Therapy

Biotech News
News Alerts

Science/General

Thu May 8 21:18:07 2008 (University of Oklahoma)
New Cancer Gene Found

Thu May 8 19:30:07 2008 (Harvard University)
Molecular Espionage Shows A Single HIV Enzyme's Many Tasks

Thu May 8 17:42:02 2008 (University of Washington)
Computer Game's High Score Could Earn The Nobel Prize In Medicine

Thu May 8 14:06:18 2008 (Rensselaer Polytechnic Institute)
Undergrad Has Sweet Success With Invention Of Artificial Golgi

Thu May 8 13:45:07 2008 (University of Pennsylvania School of Medicine)
When statins aren't enough: New trial drug points to better management of coronary heart disease

Thu May 8 12:18:08 2008 (Vanderbilt University Medical Center)
Cell's 'Power Plant' Genes Raise Vision Disorder Risk

Thu May 8 11:57:08 2008 (American Society of Plastic Surgeons)
Skin flaps deliver cancer-fighting therapy, ASPS study reveals

Thu May 8 10:30:09 2008 (American Society of Nephrology)
Vitamin D Linked To Reduced Mortality Rate In Chronic Kidney Disease

Thu May 8 10:12:16 2008 (Reuters Health)
Phone counseling helpful after cervical cancer

Science Page 2

Business

Fri May 9 04:57:09 2008 (Reuters)
UPDATE 2-Roche arthritis drug Actemra backed by fifth study

Fri May 9 01:21:09 2008 (Reuters)
UPDATE 1-Fifth study backs Roche arthritis drug Actemra

Thu May 8 23:33:09 2008 (Reuters)
Takeda to buy back up to $964 mln of own shares

Thu May 8 22:54:04 2008 (Yahoo Reuters)
Takeda sees big profit slump on Millennium costs

Thu May 8 17:33:02 2008 (Yahoo AP)
Nektar Therapeutics shares fall on wider-than-expected loss

Thu May 8 16:21:09 2008 (Reuters)
UPDATE 1-Osiris to sell unit to NuVasive for up to $85 mln

Thu May 8 15:45:02 2008 (Yahoo AP)
FDA OKs Abilify for secondary use against bipolar disorder

Thu May 8 13:57:14 2008 (Yahoo AP)
Ark. court: Cancer claim against poultry firms can proceed

Thu May 8 13:51:12 2008 (TheStreet)
Health Winners & Losers: Barr

Business Page 2

Press Releases

Fri May 9 06:21:12 2008 (GPC Biotech AG)
GPC Biotech Schedules Conference Call on May 15th to Discuss First Quarter 2008 Financial Results

Fri May 9 06:15:19 2008 (Ardea Biosciences, Inc.)
Ardea Biosciences Appoints John W. Beck Chief Financial Officer, Announces Clinical Development Progress and Reports First Quarter 2008 Financial Results

Fri May 9 06:12:23 2008 (SemBioSys Genetics Inc.)
SemBioSys announces first quarter 2008 financial and operational results

Fri May 9 04:33:02 2008 (Progenics Pharmaceuticals, Inc.)
Progenics Pharmaceuticals Reports First Quarter 2008 Results

Fri May 9 04:24:17 2008 (EUSA Pharma Inc)
EUSA Pharma Completes Acquisition Of Cytogen Corporation

Fri May 9 02:36:17 2008 (Takeda)
Takeda Successfully Completes Tender Offer for Millennium Pharmaceuticals, Inc. and Announces Subsequent Offering Period

Fri May 9 00:51:14 2008 (Northwest Biotherapeutics, Inc.)
Northwest Secures US$4.0 Million in Debt Financing

Fri May 9 00:48:14 2008 (Cytopia Limited)
Cytopia Announces Novel Anti-Cancer Drug Development Collaboration

Thu May 8 23:00:21 2008 (Halozyme Therapeutics, Inc.)
Halozyme Therapeutics Reports 2008 First Quarter Financial Results

Press Release Page 2

Biotech Market Summary
Stock Limit/Analyst Alerts

Snapshot: May 8
(Updated every 20 min)

	Change	Last
BTK	0.00 (0.00%)	747.70
DJI	52.43 (0.41%)	12,866.78
Nasdaq	0.00 (0.00%)	2,451.24

No New Coverages Reported Today.

No Upgrades Reported Today.

No Downgrades Reported Today.